ABSTRACT
Objective To explore the clinical effect of plasma exchange on postpartum HELLP syndrome.Methods From January 2014 to December 2015,44 patients with postpartum HELLP syndrome were chosen as the treatment group which received conventional treatment combined with plasma exchange.And we selected 47 patients with postpartum HELLP syndrome as the control group from January 2012 to December 2013.Serum hemoglobin(Hb),platelet(PLT),prothrombin time(PT),serum aspartate aminotransferase (AST),alanine aminotransferase (ALT),serum total bilirubin (TBIL),conjugated bilirubin(DBIL) and serum lactic dehydrogenase(LDH),blood urea nitrogen(BUN) and creatinine(Cr) level in patients with postpartum HELLP syndrome were detected before and after the treatment.The ICU stay,recovery time of PLT,ALT,AST,and LDH were compared between two group.Results After treatment,the levels of PLT,AST,ALT and LDH in the treatment group were significantly higher than those in the control group (P＜0.05).The ICU stays and the recovery time of PLU,ALT,AST and LDH in the treatment group were significantly lower than the control group (P＜0.05).Conclusion Plasma replacement can significantly improve the clinical symptoms of postpartum HELLP syndrome patients,improve the cure rate.
ABSTRACT
Hepatitis B virus (HBV) infection is a worldwide health problem and vertical transmission is the main source of chronic infection in Asian countries. Breakthrough perinatal HBV transmission occurs in 10%-15% of infants born to pregnatal women with high viral load even with appropriate postexposure immunoprophylaxis. Management of chronic hepati?tis B (CHB) during pregnancy remains a challenge, with unique issues that involve prevention of mother-to-child transmis?sion (MTCT) and safe use of antiviral therapy. Previous studies indicate that antiviral therapy with analogs (Lamivudine, Tel?bivudine or Tenofovir) may prevent vertical transmission during late pregnancy in highly viremic mothers. This article sum?marized relevant studies that antiviral therapy in preventing MTCT of hepatitis B virus.
ABSTRACT
Objective To study the relationship between the serum selenium(Se) concentra- tion and glutathione peroxidase(GSH-PX) levels in red blood cell in patients with pregnancy induced hypertension(PIH).Methods The serum Se concentration was measured by atomic absorbability assay and the GSH-PX levels were measured by cellular chemiluminescence assay.49 cases of PIH and 34 normal pregnant women were measured for serum Se concentration and GSH-PX levels in red blood cell from April,1994 to December,1994.Results The serum Se concentration and GSH-PX levels in red blood cell is different betwen PIH and control group.Compared serum Se concentration and GSH-PX levels were significant lower in the PIH patients than in the control subjects (P